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百克生物:ChangchunBCHTBiotechnologyCo.ImprovingQualityandEfficacy,

公告原文类别 2024-03-20 查看全文

Changchun BCHT Biotechnology Co.Improving Quality and Efficacy Enhancing Value Return

Corporate Action Plan 2024

Changchun BCHT Biotechnology Co(Hereinafter as "the company" or “BCHT”)

in order to implement the "investor-centered " philosophy by listed companies and protectthe interests of all shareholders of the company articulates the “Improving Quality andEfficacy Enhancing Value Return” Corporate Action Plan 2024 to further optimize the

company’s management standardize its governance enhance its market competitiveness

and protect investors' rights and interests with active measures and better returns. This

Plan is based on the company’s confidence in current operational status and future

development prospects and is mainly covered in the field of focusing on the main business

which also promoting scientific and technological innovation and consolidating

communication with investors. The main measures are as follows:

1.Focusing on the main business development capturing more market share

with better recognition

The company always persist “Devote Biotech Today Create Health Tomorrow” as

the mission since its establishment in 2004. BCHT has been engaged in research and

development manufacturing and distribution of vaccines for human use. At present the

company has marketed includes Varicella Vaccine Live; Influenza Vaccine Live Nasal

Freeze-dried; Herpes Zoster Vaccine Live etc. Among these products the domestic

market share of Varicella Vaccine Live has been in a leading position for many years

which is one of the company’s main sources of revenue; Furthermore the Influenza

Vaccine Live Nasal Freeze-dried has been included in the WHO Global Pandemic

Influenza Action Plan and also is the only live attenuated influenza vaccine administered

by nasal spray in China which greatly improves the compliance of inoculators.In January 2023 the company's zoster vaccine marketing license application was

1approved which becoming the first zoster vaccine applicable to people over 40 years old

in China. Meanwhile this vaccine breaking the monopoly by imported vaccines in

domestic zoster prevention products filling the gap of domestic zoster vaccine market

and generating a new growth point of the company’s performance.The company has established a professional marketing management team and

extensive sales channels. At present the products from BCHT have covering 31 provinces

autonomous regions municipalities directly under the Central Government in China

except Hong Kong Macao and Taiwan and are exported to overseas countries.In 2024 the company will continue to focus on its main business in that to improve

continuously leading position in its product technology and market share also to promote

comprehensively the company's core competitiveness and industry recognition focus on

to reinforce promotion and education of vaccinees and increase the products market share.Specific measures are as follows:

The company will keep an eye on industry policy and market trends and timely adjust

sales strategies according to market changes. Meanwhile the company will rely on high-

quality varieties with obvious advantages continue to publicize product quality through

professional and efficient market services actively promote the public to prevent diseases.In accordance with the annual brand promotion plan through the community and new

media such as Douyin and Meituan BCHT will systematically carry out the publicity

work of disease and disease prevention knowledge focusing on the core advantages of

listed varieties. It will help the company to establish high quality brand concept in the

public consumption consciousness.In 2024 with the launch of the company's Herpes Zoster Vaccine Live the

company's products cover both children vaccine and adult vaccine. The company will

develop differentiated marketing strategies characterized by product features and

applicable demographics. In the tasks to consolidate the market position of existing

products the company will prioritize most of all to the promotion of zoster vaccine by

taking the first-mover advantage to increase the coverage of POV. From online marketing

aspect the company will improve constantly the digital reservation system making full

use of “online reservation+ offline vaccination”. The company will persistently explore

2publicity and drainage channels such as hospitals communities and elderly care

institutions to increase investment in science popularization education improve product

market penetration and strive to return investors with better performance.

2. Accelerate progress of research pipeline and achieve innovation-driven

development

Since its establishment the company has always adhered to the development concept

of "standardization innovation focus inclusiveness and sharing". After years of

accumulation the company has established a professional research and development

system and has a relatively complete biological vaccine laboratory and pilot workshop

which has strong research and development and industrialization capabilities in the

vaccine field. Besides that BCHT has been awarded as High-tech Enterprise by Jilin

Provincial Science and Technology Agency and approved the establishment of "Jilin

Province Vaccine Science and Technology Innovation Center"; which also has been

identified as "Changchun National Biological Industry Base Vaccine Engineering

Research Center" by Changchun National Biological Industry Base; Jilin Province

Development and Reform Commission approved the company to established "Jilin

Province Vaccine Engineering Research Center"; Moreover recognized as "Provincial

Enterprise Technology Center" by Jilin Provincial Department of Industry and

Information Technology.BCHT has established five core technology platforms: Virus culture scale-up

technology platform Formulation and adjuvant technology platform Genetic engineering

technology platform Bacterial vaccine technology platform and mRNA Vaccine

Technology Platform.On the basis of independent research and development the company attaches great

importance to the construction of innovation environment carries out various forms of

industry-university-research cooperation with domestic and foreign universities and

research and development institutions establishes close research cooperation relations. It

has established technical exchange and cooperation with Jilin University Institute of

Pathogen Biology Chinese Academy of Medical Sciences and other research institutes.In addition the introduction of technology from Intravacc NIH and other international

3partners has further improved the company's technical strength and scientific research

level.In 2024 while accelerate the project of Influenza vaccine nasal live (liquid) vaccine

and Absorbed DTaP combined vaccine (three components) the following projects will be

in safeguard to ensure progress:

Promote the registration of live attenuated nasal spray influenza vaccine series.Promote the clinical research of adsorbed acellular DTaP (three components)

combined vaccine project.The phase I clinical study of fully human monoclonal antibody against rabies virus

will be completed and phase II clinical trial will be conducted.Conduct phase I clinical trials on Rabies vaccine (MRC-5 cell) for human use and

fully human monoclonal antibody against tetanus.Besides that the company will complete preclinical studies of Influenza vaccine

(split virion BK-01 adjuvant) Recombinant herpes zoster vaccine HSV-2 mRNA vaccine(herpes simplex virus-2)and Hib vaccine to submit IND to NMPA.In addition the company will continue to promote the preclinical study of multiple

research and development projects such as RSV vaccine and antibody Alzheimer's

disease therapeutic vaccine to enhance constantly its core competitiveness.While continuing to dig deep in the field of vaccine research and development the

company continues to expand the boundaries of vaccine research and development adhere

to the characteristics of equal emphasis on research and development and production

based on innovative vaccines monoclonal antibodies and other company advantages toachieve the strategic layout of “production generation research and developmentgeneration reserve generation” to get better meet the market demand in the future.

3.Improve corporate governance and operational quality and efficiency

The company attaches great importance to the sound governance structure and the

effectiveness of the internal control system. In 2023 The Company has revised a total of

13 governance systems including the “Articles of Association” the “IndependentDirector Work System” the “Related Party Transaction System” and the “Raised FundsManagement System” in accordance with the relevant governance rules of the China

4Securities Regulatory Commission and the Shanghai Stock Exchange. The company

closely integrates the corporate development strategy with the practice of business

sustainability and attaches great importance to the guiding and promoting role of ESG in

corporate governance and production operations. In 2023 BCHT has released its first

environmental social and governance (ESG) report (the third corporate social

Responsibility report). In the future the company will continue to fulfill its corporate

social responsibility take into account the interests of shareholders employees customers

and other relevant parties in operation and management and promote the deep integration

of ESG concepts into corporate strategic decision-making daily functional management

and business operations. The same year the company won the "Top 50 Science and

Technology Leaders" award in the "First China New Cup ·ESG Golden Bull Award"

organized by China Securities Journal; In the Securities Market Weekly's "Crystal Ball

Award for Listed Companies 2023" the company won the "Most Socially Responsible

(ESG) Listed Company" award.

In 2024 the Company will strengthen the implementation and process supervision

of the new system the revised system and the important system by improving the

efficiency of operation. At the same time the company will formulate systematic publicity

and implementation plans according to the execution. The company will also

comprehensively review the original management system focusing on the level of internal

control system and the matching of information system. Through these measures the

company will provide rigorous and orderly system and process support for the operation

of the company. Further clarify the responsibilities and authority of relevant departments

form a benign internal drive for enterprise development and build a solid foundation for

the sustainable development of enterprises.Besides as “directors supervisors and senior managers” play a vital role in corporate

governance the Company will establish a continuous tracking and publicity mechanism

for regulatory regulations and developments in 2024 and actively organize directors

supervisors and senior managers to participate in various trainings held by CSRC

Shanghai Stock Exchange Pujiang Auditorium local securities regulatory Bureau and

other regulatory bodies to ensure that these key roles are familiar with the knowledge of

5the securities market. Keep abreast of relevant laws and regulations constantly improve

the awareness of risk and self-discipline and lead the company to sustainable high-quality

development.

4. Maintain steady performance growth and share the results of corporate

development with investors

The company firmly establishes the investor-based concept continuously focuses on

the main business consolidates the dominant position of the industry strives to improve

the company's performance and makes full use of cash dividends and other measures to

share the dividends of the company's development with all shareholders.The company achieved operating income of 1824.69 million yuan in 2023

compared with 1071.45 million yuan in the same period of last year that is an increase

of 753.24 million yuan grow by 70.30%;Also the net profit attributable to shareholders

of listed companies was 501.01 million yuan in 2023 compared with 181.54 million yuan

in the same period of last year it is an increase of 31.95 million yuan the rate of increase

is 175.98%;Then the net profit attributable to shareholders of listed companies after

deducting non-recurring gains and losses amounted to 493.36 million yuan compared to

166.75 million yuan in the same period of last year an increase of 326.60 million yuan

or 195.86%.Since its listing the company has carried out stable and sustainable cash dividends

and has paid cash dividends every year in strict accordance with the profit distribution

policy formulated in “the Articles of Association.” Up to now the company's total

accumulated cash dividends reached 103.21 million yuan of which the 2022 cash

dividend amount accounted for 34.11% of the company's net profit attributable to

shareholders of listed companies in the year.On March 18 2024 the Company held the 23rd meeting of the fifth Board ofDirectors and unanimously approved “the Motion on 2023 Annual Profit DistributionPlan”. In 2023 based on the total share capital the Company intends to pay cash dividends

of 1.5 yuan (including tax) for every 10 shares and cash dividends of 61926104.70 yuan

(including tax). The company's 2023 profit distribution plan has yet to be submitted to the

shareholders' meeting for consideration.

6In 2024 BCHT will formulate a scientific production plan to ensure the orderly

production and approval of vaccine products. Actively carry out the process optimization

and improvement of existing products strictly implement the product life cycle quality

management continue to promote the lean development of production quality and ensure

that products are stable timely and fully supplied to the market.The company will continue to balance the dynamic balance between performance

growth and shareholder returns according to its own development stage and the capital

needs of key research and construction projects. Besides that BCHT will also explore the

feasibility of medium-term cash dividends.adhere to the "long-term stable and sustainable" shareholder return mechanism and

share the company's development results with shareholders.

5. Strengthen communications with investors and improve the quality of

information disclosure

Since the listing of the Company the directors supervisors and senior management

have attached great importance to investor relations management ensuring that the

information disclosure is true accurate complete and timely and treating all shareholders

and potential investors of the company fairly. BCHT will always following the principles

of honesty high efficiency low consumption and interactive communication through

compliance and efficient means to promote the positive relationship between the company

and investors enhance investors' further understanding and familiarity with the company

under the premise of stable and good performance which also establish a stable and high-

quality investor base so as to obtain long-term market support. In 2023 the company

issued a total of 104 announcements and related disclosure documents including 13

announcements related to investor relations management accounting for 12.5% of the

total announcements in the year.The office of the Board of Directors is a specialized department for the company to

communicate with investors since listing through "SSE E Interactive" investor email

and the telephone of the office of the Board of Directors truthfully and sincerely reply to

investors' questions the response rate of investor questions is 100%. Based on this effort

the company establish a benign mechanism with investors.

7In terms of information disclosure through the comprehensive evaluation of the

Shanghai Stock Exchange the company's information disclosure work evaluation results

in the 2022-2023 year of information disclosure work evaluation of listed companies on

the Science and Technology innovation Board of the Shanghai Stock Exchange are A-

level. In addition the company also won the Jilin Provincial Securities Industry

Association "2023 Outstanding Practice of Investor Relations management Listed

Company in Jilin".In 2024 the Company will continue to strictly comply with laws regulations and

regulatory requirements and fulfill its information disclosure obligations truthfully

accurately completely timely and fairly including the following aspects:

a. The simplicity and clarity of information disclosure and its visualization

In 2024 BCHT will make full use of the online methods with greater coverage and

publicity influence take the company's website and public number as the publicity carrier

pass on the company's information to the majority of investors through multiple channels

and forms and constantly improve the transparency of the company's information

disclosure. Besides that during the company releases periodic reports the company will

also interpret the periodic reports in visual forms such as performance presentations and

graphic presentations and help investors understand the company's operating results more

intuitively and more simply and discover the company's value through visualization.b. Smooth communication channels for investors

The company plans to arrange a series of investor relations activities hold no less

than 4 performance presentations and the chairman/general manager will lead the team

to participate in investor interaction.In addition we will actively participate in the strategy meeting organized by the

organization invite investors to visit the company's vaccine production base offline more

than 10 times and have face-to-face communication with various investors to enhance

investors' understanding of the company's development strategy and business conditions.

6. Strengthen the responsibility of management and share the interests with

shareholders

The company formulated the "Executive Compensation and Assessment

8Management Measures” and combined with the initial equity incentive plan implemented

after listing formulated the "2022 Restricted Stock Incentive Plan Implementation

Assessment Management Measures" the relevant management measures stipulate that the

performance assessment of the company's senior management personnel and incentivize

business backbone should be combined with their own job responsibilities. Conduct

comprehensive evaluation on the company's overall development goals such as R&D

project progress sales customer development production plan product quality and

safety guarantee so as to effectively link the compensation and equity incentive

ownership of senior management personnel and business backbone to the company's

operating performance and ensure the company's healthy sustainable and stable

development.In 2023 based on the firm confidence in the company's future development prospects

and the high recognition of medium and long-term investment value in order to

effectively safeguard the interests of small and medium-sized investors and the stability

of the capital market boost the confidence of the majority of investors Mr. Kong Wei a

shareholder director and general manager who holds more than 5% of the Company's

shares increased his holdings of 187913 shares of the Company by centralized bidding

in April 2023 with an additional holding amount of 9990125.98 yuan. In October Mr.Kong Wei voluntarily issued the "Commitment Letter on not reducing the Company's

shares in the next six months" promising not to reduce all the shares of the Company held

by him in any way during the period from October 18 2023 to April 17 2024.In 2024 the company will strictly follow the requirements of relevant laws

regulations and normative documents strengthen the responsibility of the management

always adhere to the principle of good faith business improve the governance structure

with complete functions and mutual checks and balances establish a clear division of

responsibilities standardized and efficient work processes and procedures clarify the

responsibilities and objectives of all levels and departments and form a more perfect

corporate governance mechanism.It shall abide by the Company Law the Securities Law relevant laws and regulations

the rules and normative documents of the China Securities Regulatory Commission and

9the restrictive provisions on the transfer of shares in the rules of the stock exchange

strictly regulate the trading behavior of directors supervisors and high officials on the

company's stocks and put an end to violations such as short-term trading insider trading

and window period trading of the company's stocks.This action plan of “Improving Quality and Efficacy Enhancing Value Return” is

based on the current situation of the company and does not constitute a performance

commitment. In the future it may be affected by domestic and international market

environments policy adjustment and other factors with certain uncertainties. Investors

are advised to invest cautiously and be attention to investment risks.The Company will continue to evaluate the specific implementation of the corporate

action plan of “Improving Quality and Efficacy Enhancing Value Return” fulfill the

obligation of information disclosure in a timely manner actively practice the

responsibilities of listed companies and strive to actively repay the attention and trust of

investors with good performance and standardized corporate governance.Hereby notice.Changchun BCHT Biotechnology Co.Board of Directors

20-March-2024

10

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