“”“”

“”“”

20201185

600013.99

839400000.0061758000.00

777642000.00

79833781.034506826.42

764073045.39

2020713

[2020]

210Z0012

1231

839400000.00

61758000.00

777642000.00

15233415.00

12651300.00

130000770.02

424003211.69

13657285.00

33329317.31

110000000.00

56000000.00

42476589.70

111002.49

123135132288.19

2020630

32050174513609066666

2020630

9550880058239300203

32050159524609999996

2020630

90160188000125327

22022119

2022126

32050174513600001886

2022221

32050159524609111111

202233

9550880058239300203

32050174513600001886

20231027

1001300001151309

1231

320501745136000018861442.27

32050174513609066666119.43

90160188000125327800.22

32050159524609999996946.09

33205015952460911111110.82

1001300001151309194.64

3513.46

12300.00

2300.00

4000.002023/9/21/1/194000.0040.00

7000.002023/10/13/1/67000.0037.55

2000.002023/11/27/2/262000.0012.47

2000.002023/11/29/2/292000.0012.60

1000.002023/12/29/1/261000.001.91

0441030B 2500.00 2023/11/8 /2/8 2500.00 18.63

3000.002023/12/29/4/13000.0022.41

6000.00/1/17/3/296000.0033.14

2000.00/1/18/4/182000.0012.47

4000.00/1/29/6/44000.0040.92

2000.00/3/1/5/312000.0012.72

2000.00/3/11/6/112000.0012.60

0081030B 1500.00 /2/22 /5/22 1500.00 10.54

5000.00/4/3/6/285000.0031.81

2000.00/4/16/7/102000.0013.04

41000.00/4/23/7/171000.006.52

0211030M 1500.00 /5/23 /8/23 1500.00 10.16

1000.00/5/27/6/301000.002.34

1000.00/6/12/10/111000.008.23

2000.00/6/11/9/112000.0012.91

1000.00/6/28/9/271000.005.73

4000.00/7/12/8/124000.007.11

1000.00/7/26/8/261000.001.39

2500.00/8/14/11/152500.0016.56

0340000P 1000.00 /9/2 /12/3 1000.00 5.36

2000.00/9/4/12/42000.008.23

1000.00/10/12/11/121000.002.12

1000.00/11/15/12/151000.001.97

2000.00/12/132025/3/13-

1000.00/12/202025/3/20-

40501030A 600.00 /12/16 2025/3/16 -

2000.00/12/172025/3/31-

A

51231

55400.401788.47

1365.733332.93

61887.531

2020819

13000.08523.3413523.42

[2020]210Z0076

415

1.50

12

6139

39185000.004000.002000.00

6325

2.5

124142025413

1231

56003626.3671.37

1231

1365.732023314

3332.93

71231

1231

2——

1——

81

77764.209989.85

26158.7561887.53

33.64%

(%)(4)

(1)(2)(2)/(1)

(3)(2)-(1)

ACC008III/IV

9020.009020.009020.002126.947930.29-1089.7187.92202512

0.009500.009500.00192.101053.01-8446.9911.0820256

III 0.00 10050.00 10050.00 605.18 7655.12 -2394.88 76.17 2026 12

0.007010.007010.002489.465559.10-1450.9079.30202712

HIV 0.00 3700.00 3700.00 1167.64 1462.00 -2238.00 39.51 2026 12

1082.3520233

20330.0020330.0020330.003280.3216740.88-3589.122022

1

ACC007III/IV

5610.000.000.000.00

ACC006BCCII

3340.000.000.000.00

ACC006

7010.000.000.000.00

II

ACC006PD-1 II

5260.000.000.000.00

ACC010I/II

5340.000.000.000.00

3700.000.000.000.000.000.00

15000.0015000.0015000.00128.2115000.000.00100.00

74610.0074610.0074610.009989.8555400.40-19209.60

3154.203154.203154.200.003154.200.00100.00

0.000.000.000.003332.933332.93

1177764.2077764.2077764.209989.8561887.53-15876.67

1 ACC008 III/IV HIV ACC008 2022 12 30

IPO

IPO

2023 ACC008 2023 7 31

20251231202381

2 III

ICH S1A

2021 12 ICH S1B R1

WoE Weight of Evidence

()

2022 8 ICH

2022 6 CDE WoE

2022 8 CDE 2023 3

2023731

20261231202381

3 2021 I

I 2022 I

CDE

12CDE

2023727

-

2023

415

2025630

416

2025630

415

“”

2025 6 30 CDE

2025630

415

1.50

12

613939185000.004000

2000

13325

2.5

12

4142025413

12315600

3626.3671.37

1797.30431.5712

311365.732023314

2023331

3332.93

1202333589.121204.34

2384.782384.783332.93948.15

2 ACC007 III/IV 2021 8 26 2021 9 14 2021

III 5610.00 10050.00

ACC007 III/IV 4101.25

III

14